Complete nucleotide sequence of the membrane form of the human IgM heavy chain.
نویسندگان
چکیده
We have cloned and sequenced a full length human immunoglobulin M chain cDNA of the membrane bound form. The variable region, nucleotides 119 to 529, is a member of the VHj family. Nucleotides 530 through 1831 encode the heavy chain constant region, which shows 73% identity to mouse and 79% identity with rabbit heavy chain sequences (1). Differences from previously published DNA and protein sequences, of the human constant gene, are underlined (2, 3). Exon boundaries are indicated by arrows.
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عنوان ژورنال:
- Nucleic acids research
دوره 18 14 شماره
صفحات -
تاریخ انتشار 1990